Effect of Sterculia quadrifide Extract R.Br. Against Free Radical In Liver Organs Oreochromis niloticus Due to Heavy Metal Pollution

Janes Bastian Selly, Abdurrouf Abdurrouf, Unggul P. Juswono

Abstract


Sterculia quadrifida R.Br. is known with the name of Faloak. It is a plant whose bark has been containing several natural antioxidant compounds. Research shows that antioxidant compounds of Faloak extract can reduce free radicals content in liver organ of nila fish (Oreochromis niloticus) that is contamined by metals such as Pb, Cd and Hg. The concentration of metals is directly proportional with free radicals content of the organ, but free radicals content is inversely proportional with the concentration of faloak extract. Result of research indicates that faloak concentration of 16,00mg/mL is the most effective concentration in reducing free radicals content in liver organ of nila fish. Type and content of free radicals in the organ are identified with Electron Spin Resonance (ESR) test.

 


Keywords


antioxidant; ESR; heavy metals; liver organ of nila fish; free radicals.

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References


Pala, F.S., & Kymet, T. (2007), Free radicals: Our enemies or friends? Advances in Molecular Biology, (I), 63-68.

Syaifudin, M. (2005), Indikator biokimia sel terhadap radiasi pengion. Buletin ALARA 6(3), 125-131.

Berlianti, N.A. (2014), Studi tentang pengaruh limbah pencemar terhadap kandungan radikal bebas pada organ insang ikan nila (Oreochromis niloticus). Jurnal Natural B, 2(4), 355-359.

Darmono (2006), Lingkungan Hidup dan Pencemarannya. Jakarta: Universitas Indonesia (UI-Press)

Siregar, Y.I., Zamri, A., Putra, H. (2012), Penyerapan timbal (Pb) pada sistem organ ikan mas. Jurnal Ilmu Lingkungan. Universitas Riau, Pekanbaru.

Siswadi, Dani H.S., Grace S.S., and Heny R. (2013), The potency of faloak’s (Sterculia quadrifida R.Br 1844) active compounds as natural remedy. Kupang Forest Research Institute.

Droge, W. (2002), Free radicals in the physiological control of cell function. Physiol Rev 82:47-95.

Donuata, P.B. (2014), Pengaruh aparan radiasi gamma dan pemberian ekstrak bagian putih semangka (Citrullus vulgaris Schrad) terhadap kesehatan ginjal pada hewan coba mencit. Jurnal Natural B, 2(4), Oktober 2014.

Chen, J.W., Zhu, Z.Q., Hu, T.X., Zhu, D.Y. (2002), Structure-activity relationship of natural flavonoids in hydroxyl radical-scavenging effects. Acta Pharmacol Sin. 2002 Jul: 23(7): 667-72.

Perron, N.R., & Brumaghim, J.L. (2009), A review of antioxidant mechanism of polyphenol compounds related to iron

binding. Cell Biochemistry and Biophysics, 53(2), 75-100.

Grazul, M., & Budzisz, E. (2009), Biological activity of metal ions complexes chromones, coumarins and flavones. Coordination Chemistry Reviews, 253, 2588-2598.




DOI: http://dx.doi.org/10.21776/ub.natural-b.2015.003.02.11

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